The authors research 182 patients with appendectomia (55 males and 127 women) for their blood group belonging to the systems ABO and Rhesus factor (based on same data about family predisposition to appendicitis). The result are compared to the data of the blood group belonging to the both systems in 1080 Bulgarians. These data don't show any significant differences between two groups not either related to blood group system ABO (p>0.05, K=3, γ2 = 1,9072) not to Rhesus factor (p>0.05, K=l, γ2 =1,6537).