Migration is one of the factors that change genetic structure of populations. The war in this region left many consequences that shall be the subject of research and analyses in different sciences for a long time. Distribution of ABO and Rh blood types, being significant characteristics of human populations, has been studied several times, but major migration of people in this region in the last decade of 20th century and many lost lives oblige us to analyze these characteristics again. The data were gathered in Doboj region (Doboj, Petrovo, Modriča, Šamac, Brod, Teslić, Derventa) and compared both to known data for this region and to new data for other regions. The observed changes in blood types distribution shall soon give more realistic picture of changes in alleles' frequencies. .