Inborn heart failure is defined as structural abnormalities of cardiovascular system present at the very birth and manifested: immediatelyin the early neonatal period, after several weeks or months. Incidence rate is 6-8 cases in 1000 live born babies. 30% of all inborn failures go to inborn heart failures. They are divided into: failures with cyanosis and failures without cyanosis; failures with murmur and failures without murmur. Etiology is multifactorial. The symptoms are: cyanosis, fatigue, tachypnea, dyspnea, slow advance of body mass, frequent respiratory infections. Retrospective analysis of the protocol of live born babies and the list of newborns in Maternity hospital in Prokuplje for period from January 1, 1994 to December 31, 2008 shows that 57 babies were born with an inborn heart failure. All of them had heart murmur in the first six days of life. The increase in the newborns with inborn heart failure in the last five years is evident. The failure is prevalent in female babies. Such babies deserve great attention of medical staff and their parents and surrounding because 1-2% of all organic heart conditions go to congenital anomalies of the heart. Since they frequently result in death, they need to be duly discovered and adequately diagnosed and treated. .