MNS system blood groups examined on blood donors. The tests were made on the sample of 1200 donors for M, N, S and s alels. The analyses were made through standard procedures and the data were statistically processed. Results pointed that in population of Vojvodina s alel is the most frequent alel, most frequent genotype is ss, MN and Ss, the most frequent phenotypes are MNss, MNSs and NNss. Frequences of alels, genoypes and phenotypes in Vojvodina are rather similar to coresponding values in other Serbia, Balcan and European populations. The study has confirmed that the population of Vojvodina is specific and it represents a contribut ion to the analysis of the genetic variability of population in Vojvodina. .