The goal of this research was to overview concentration of aceticisalic acid (ASK), applied perorally by electrophoresis (EF) into the knee joint for sport injuries of 8 parachutists with damaged meniscus along with determination of knee width and angle of its movement. The concentration of the given medicine was quantified by methods of liquid-mass spectrometry (HPCL) while by means of meter and gravitational angle-meter the difference was determined according to width of healthy and injured knee and amplitude of movement. Research results were tested by means of Student t-test for small pair of examples, and we observed a significant amount of drug p<0, 001, administered per a short period of time into EF in meniscus compared to a five-day peroral application of the drug, and therefore higher concentration in synovial liquid compared to meniscus. The difference between central width of healthy and injured knee and amplitude of movement of injured joint for both groups of examiners was compared during the period of 5 days according to EF. We observed statistically significant improvement in movement and smaller difference in the width of healthy tissue compared to injured tissue of the knee in the group with EF, with the importance of p<0,005. Conclusion: The distribution of drug by electrophoresis into the knee joint, significantly affects reducing of inflammation and prevention of anatomical remodeling of the knee joint, along with its higher functionality compared to peroral application of drug.
