Genetic analysis of allelic variants, single-step mutations, three allelic variants of the 15 STR loci in the population of Northeast Bosnia

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Title

Genetic analysis of allelic variants, single-step mutations, three allelic variants of the 15 STR loci in the population of Northeast Bosnia

Subtitle
Author

Vesna, Hadžiavdić, Izet, Eminović, Damir, Marjanović, Hajrija, Hamidović, Adisa, Ahmić, Aldijana, Tursunović

Journal

Glasnik Antropološkog društva Srbije

Volume
Issue

48

Start page

89

End page

96

ISSN

1820-7936

ISBN
DOI

10.5937/gads1348089H

URL

http://scindeks.ceon.rs/article.aspx?query=ISSID%26and%2612263&page=0&so...

Date

2013-2021/11/03/10:57:36

Abstract

Diversity of nuclear DNA microsatellite markers were analyzed in a reference sample of the population of northeast Bosnia. 437 samples taken from unrelated individuals were processed and three samples of paternity proof were shown. Detection effectiveness profile of the research, points to a valid choice of method of extraction, amplification and genotyping STR loci with PowerPlextm16. Genetic analysis of allelic variants of the 15 STR loci detected 17 samples determined as microvariants. Samples were divided into 15 different allelic variants at 7 different loci, and are: in locus D7S820, D16S539, D3S1358, D18S51, PENTA D, PENTA E and in locus vWA. Genetic analysis of mutations in cases of paternity determined three examples of single-step mutations in the loci FGA, Penta D and D3S1358. Genetic analysis of observed STR loci detected three allelic variant of genotype combination 7/10/11.3 in locus D7S820 Type II.

Keywords